SmartSorb™ Technology

The absorption problem, solved for supplements.

Liquids, sprays, and gummies with bioavailability that finally matches the label. SmartSorb™-encapsulated caffeine appeared in the bloodstream in under 15 minutes, with significantly higher peak concentration than free caffeine. Similar results observed with CBD and THC.

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SmartSorb nanosphere releasing encapsulated hydrophilic and lipophilic ingredients

Even great formulations underdeliver when they never get absorbed.

Brand owners formulate with premium vitamins, botanicals, and functional actives. Consumers pay premium prices to use them. But most oral actives are broken down before they reach the bloodstream, which means the label claim and the lived experience don't match.

<7%
of a functional ingredient actually reaches its target in the body, on average.

The Technology

A smarter delivery platform for smarter formulations.

SmartSorb™ is a patented, all-natural nano-encapsulation technology that solves the absorption problem at the molecular level. It encapsulates active ingredients inside a self-assembling lipid sphere smaller than 200 nanometers, releasing payload exactly where it needs to go: into the bloodstream, into cells.

Onset in Under 15 Minutes

Measured bloodstream detection time for encapsulated caffeine.

Higher Bioavailability

Up to 4× more active delivered versus unencapsulated formats.

All-Natural & GRAS

Water, ethanol, lecithin. Clean-label by default.

Smaller Effective Dose

Sustained release means label claims consumers actually feel.

Oral Bioavailability Study

SmartSorb™-encapsulated caffeine appeared in the blood in under 15 minutes, with significantly higher peak concentration. Similar results observed with CBD and THC.

<15 min
time to bloodstream detection

Delivery Precision

Nanoparticles engineered from 20 nm to 400 µ depending on the use case, stable across pH 3.0 to 8.0 and heat/cold/freeze cycles.

4× more active
active ingredient delivered vs. unencapsulated

Built For Supplements

Bioavailability that finally matches the label.

Supplement and wellness brands are a core licensing focus for NuVessl, with next-generation delivery for vitamins, botanicals, peptides, and functional actives, with the bioavailability data to back the label claim.

Formulation vials, representing SmartSorb oral supplement formats

Oral Wellness Supplements

Liquids, sprays, and gummies with bioavailability that finally matches the label. Faster onset, sustained release, and a smaller effective dose.

NuVessl R&D lab where supplement formulations are developed

R&D Support, Not Just Supply

Direct support from NuVessl's R&D team during formulation, scale-up, and commercialization, backed by 24 years of delivery science.

FAQ

Answers to the questions partners ask first.

SmartSorb™ is a patented nano-encapsulation technology that improves the absorption, onset, and bioavailability of active ingredients in oral supplement products. It uses self-assembling lipid nanoparticles made from three GRAS components: water, ethanol, and lecithin, carrying water-soluble and oil-soluble actives in the same particle and releasing them at a controlled rate.

SmartSorb™ has been validated with more than 100 active ingredients, including vitamins (A, C, D, E, B-complex), caffeine and other stimulants, cannabinoids, amino acids, and electrolytes. Our R&D team can run a feasibility assessment for ingredients not yet on that list.

Yes. SmartSorb™ is built from three GRAS components: water, ethanol, and lecithin, with no synthetic surfactants or animal-derived ingredients in its base formulation, suitable for clean-label, all-natural, and Non-GMO positioning.

Schedule a meeting for a 30-minute introductory call to walk through your formulation and timeline, or use the contact form below and we'll respond personally within one business day.

Contact

Get started with SmartSorb™.

Whether you're ready to formulate, have questions, or want to see SmartSorb™ in action, we're here to help. We'll respond personally, usually within one business day.

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