SmartSorb™ Technology
The absorption problem, solved for supplements.
Liquids, sprays, and gummies with bioavailability that finally matches the label. SmartSorb™-encapsulated caffeine appeared in the bloodstream in under 15 minutes, with significantly higher peak concentration than free caffeine. Similar results observed with CBD and THC.
Schedule a Meeting
Even great formulations underdeliver when they never get absorbed.
Brand owners formulate with premium vitamins, botanicals, and functional actives. Consumers pay premium prices to use them. But most oral actives are broken down before they reach the bloodstream, which means the label claim and the lived experience don't match.
The Technology
A smarter delivery platform for smarter formulations.
SmartSorb™ is a patented, all-natural nano-encapsulation technology that solves the absorption problem at the molecular level. It encapsulates active ingredients inside a self-assembling lipid sphere smaller than 200 nanometers, releasing payload exactly where it needs to go: into the bloodstream, into cells.
Onset in Under 15 Minutes
Measured bloodstream detection time for encapsulated caffeine.
Higher Bioavailability
Up to 4× more active delivered versus unencapsulated formats.
All-Natural & GRAS
Water, ethanol, lecithin. Clean-label by default.
Smaller Effective Dose
Sustained release means label claims consumers actually feel.
Oral Bioavailability Study
SmartSorb™-encapsulated caffeine appeared in the blood in under 15 minutes, with significantly higher peak concentration. Similar results observed with CBD and THC.
Delivery Precision
Nanoparticles engineered from 20 nm to 400 µ depending on the use case, stable across pH 3.0 to 8.0 and heat/cold/freeze cycles.
Built For Supplements
Bioavailability that finally matches the label.
Supplement and wellness brands are a core licensing focus for NuVessl, with next-generation delivery for vitamins, botanicals, peptides, and functional actives, with the bioavailability data to back the label claim.

Oral Wellness Supplements
Liquids, sprays, and gummies with bioavailability that finally matches the label. Faster onset, sustained release, and a smaller effective dose.

R&D Support, Not Just Supply
Direct support from NuVessl's R&D team during formulation, scale-up, and commercialization, backed by 24 years of delivery science.
FAQ
Answers to the questions partners ask first.
SmartSorb™ is a patented nano-encapsulation technology that improves the absorption, onset, and bioavailability of active ingredients in oral supplement products. It uses self-assembling lipid nanoparticles made from three GRAS components: water, ethanol, and lecithin, carrying water-soluble and oil-soluble actives in the same particle and releasing them at a controlled rate.
SmartSorb™ has been validated with more than 100 active ingredients, including vitamins (A, C, D, E, B-complex), caffeine and other stimulants, cannabinoids, amino acids, and electrolytes. Our R&D team can run a feasibility assessment for ingredients not yet on that list.
Yes. SmartSorb™ is built from three GRAS components: water, ethanol, and lecithin, with no synthetic surfactants or animal-derived ingredients in its base formulation, suitable for clean-label, all-natural, and Non-GMO positioning.
Schedule a meeting for a 30-minute introductory call to walk through your formulation and timeline, or use the contact form below and we'll respond personally within one business day.
Contact
Get started with SmartSorb™.
Whether you're ready to formulate, have questions, or want to see SmartSorb™ in action, we're here to help. We'll respond personally, usually within one business day.
Already know we're a fit?
Skip the form and book directly.
Schedule a Meeting- Brent Bieber, Co-CEObrent@nuvessl.com