SmartSorb™ Technology
The absorption problem, solved for skincare.
SmartSorb™ penetrates the stratum corneum with consistent, measurable delivery, the basis for clinically credible serums, creams, and dermaceuticals. In comparative studies, SmartSorb™-formulated CBD penetrated 3× deeper into skin and delivered 4× more active than unencapsulated CBD.
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Even great actives fail when they can't get past the stratum corneum.
Brand owners formulate with premium peptides, botanicals, and cannabinoids. Consumers pay premium prices to use them. But most topical actives are filtered out or never penetrate deep enough to perform. That's an absorption problem, not a formulation problem.
The Technology
A smarter delivery platform for smarter formulations.
SmartSorb™ is a patented, all-natural nano-encapsulation technology that solves the absorption problem at the molecular level. It encapsulates active ingredients inside a self-assembling lipid sphere smaller than 200 nanometers, releasing payload exactly where it needs to go: into skin, into cells.
Rapid + Sustained Release
Engineered release timing matched to the formulation's use case.
Up to 3× Deeper Penetration
Measurable improvement into the epidermis versus standard formulations.
All-Natural & GRAS
Water, ethanol, lecithin. Clean-label by default.
Drops Into Existing Lines
No specialized equipment required to manufacture.
Topical CBD Penetration Study
SmartSorb™-formulated CBD penetrated deeper into skin and delivered more active versus standard formulations.
Delivery Precision
Nanoparticles engineered from 20 nm to 400 µ depending on the use case, stable across pH 3.0 to 8.0.
Built For Skincare
Topicals that penetrate, perform, and stand up to clinical scrutiny.
Skincare and dermaceutical brands are a core licensing focus for NuVessl. The platform is built for formulators who compete on efficacy data, not just ingredient lists.
Clinical Skincare & Topicals
Penetrates the stratum corneum and into the epidermis with consistent, measurable delivery, the basis for clinically credible serums, creams, and dermaceuticals.
R&D Support, Not Just Supply
Direct support from NuVessl's R&D team during formulation, scale-up, and commercialization, backed by 24 years of delivery science.
FAQ
Answers to the questions partners ask first.
SmartSorb™ is a patented nano-encapsulation technology that improves the absorption, onset, and bioavailability of active ingredients in topical products. It uses self-assembling lipid nanoparticles made from three GRAS components: water, ethanol, and lecithin. Unlike emulsions, which suspend ingredients in a mixture, SmartSorb™ encapsulates them, carrying water-soluble and oil-soluble actives in the same particle, protecting them from degradation, and releasing them at a controlled rate.
NuVessl licenses SmartSorb™ to skincare and dermaceutical brand owners and their manufacturing partners. A typical engagement includes access to the patent portfolio, supply of the SmartSorb™ precursor ingredient, and direct R&D support. Cost varies by formulation and is discussed on a call rather than published as a single figure.
Yes. SmartSorb™ is built from three GRAS components: water, ethanol, and lecithin, with no synthetic surfactants or animal-derived ingredients in its base formulation, and is suitable for clean-label, all-natural, and Non-GMO positioning.
Schedule a meeting for a 30-minute introductory call to walk through your formulation and timeline, or use the contact form below and we'll respond personally within one business day.
Contact
Get started with SmartSorb™.
Whether you're ready to formulate, have questions, or want to see SmartSorb™ in action, we're here to help. We'll respond personally, usually within one business day.
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Schedule a Meeting- Deborah Duffey, COOdeborah@nuvessl.com